IJBPS Table of Content: September 1(2)

Full Length Research


Nathan Meka1, 2*, Assefa Sergawie1, and Khalid Siraj2pp. 7 - 13

The study of the Electrochemical Deterioration of Human Teeth in Oral Cavity and the Role of Saliva



This work is carried out to confirm the existence of the surface potentials in extracted tooth by electrochemical method. The surface potentials were measured between enamel crown’s buccal side and tooth root. Surface potentials examined in all the teeth in the presence of KCl. It is found that potential increased with increasing KCl concentration after acid corroded. The results suggest that potentials can be affected by the surrounding electrolytes and establish an electrical double layer. It is also found that on passing electric current through enamel causes degradation.

Keywords: Surface potential, electrochemistry, corrosion, enamel, fluoride ion.


Offor, C.E.  pp. 14 - 18

Comparative Analyses on the Effects of Ethanol Leaf-Extracts of Vernonia amygdalina and Azadirachta indica on Lipid Profile in Albino Rats



The comparative analyses on the effects of ethanol leaf-extracts of Vernonia amygdalina and Azadirachta indica on lipid profile were conducted using albino rats. The albino rats were grouped into seven (A, B, C, D, E, F and G) containing ten rats per group. Groups A, B, and C were administered Vernonia amygdalina extract by oral intubation at the doses of 200, 400 and 600 mg/kg body weights respectively for two weeks with corresponding doses of the extract of Azadirachta indica administered to groups D, E and F. Animals in group G served as the control. The serum levels (mg/dl) of total cholesterol, LDL-cholesterol, HDL-cholesterol and triacylglycerol were studied spectrophotometrically. Total cholesterol, triacylglycerol and LDL-cholesterol levels were significantly (p<0.05) reduced by both extracts while HDL-cholesterol levels were increased significantly. There were dose-dependent reductions in the body weights of all the animals that received the extracts. The results showed that the leaf-extract of Vernonia amygdalina was more effective as a cardioprotective agent than that of Azadirachta indica.

Keywords: Ethanol leaf-extracts, Vernonia amygdalina, Azadirachta indica, lipid profile and albino rats.